Oxford University Press, 1996, Red Cloth, Book Condition: Near Fine, Dust Jacket Condition: No Jacket, First

gilt titles spine & front; illustratwed by b/w. photo's. charts & diagrams; "the term 'amyloidosis' describes a group of diseases characterized by extracellular deposition of a fibrillar protein, amyloid, (Cohen 1967; Glenner et al. 1970). The growing mass of amyloid fibrils associates with plasma and extracellular matrix proteins and proteoglycans to form amyloid deposits. The amyloid deposits bind Congo red stain and. give a green birefringence in polarized light, which is the most common histological criterion used for the presence of amyloid deposits in tissues (Cooper 1974). Characteristic fibrils of 7-10 nm diameter with a random twist are seen using electron microscopy, and a B-pleated sheet configuration is viewed with X-ray crystallography (Cohen and Calkins 1959). Amyloid fibrils are known to be highly insoluble under physiological conditions and resistant to normal degradative processes in vivo, and therefore when they deposit within the physiological environment of the cell, thereby replacing normal tissue constituents, the function of the affected organ is often disturbed (Glenner 1980)". as new condition; including index - 282 pages. A HEAVY BOOK WHICH WILL REQUIRE ADDITIONAL POSTAGE Size: 4to - over 9¾" - 12" tall. Quantity Available: 1. Category: Medicine & Health; Kidney Disease; Renal Failure; Nephrology; Medicine & Health. ISBN: 0192624946. ISBN/EAN: 9780192624949. Inventory No: MDC00034.